Lumiprobe 磺酸基CY 3马来酰亚胺 Sulfo-Cyanine3 maleimide

发表于由

Lumiprobe 磺酸基CY 3马来酰亚胺 Sulfo-Cyanine3 maleimide

Sulfo-Cyanine3 maleimide is a water soluble, thiol reactive dye for the labeling with hydrophilic sulfo-Cyanine3 fluorophore. This is an analog of Cy3® maleimide.

This product is recommended for the labeling of antibodies and other labile proteins in mild, purely aqueous conditions. The dye is water soluble and does not require use of organic co-solvent.

A non-sulfonated Cyanine3 maleimide

Sulfo-Cyanine3 maleimide

General properties

Appearance: red powder
Molecular weight: 776.96
CAS number: 1656990-68-9
Molecular formula: C36H41KN4O9S2
IUPAC name: 3H-​Indolium, 2-​[3-​[1-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​3,​3-​dimethyl-​5-​sulfo-​2H-​indol-​2-​ylidene]​-​1-​propen-​1-​yl]​-​1,​3,​3-​trimethyl-​5-​sulfo-​, inner salt, potassium salt
Solubility: soluble in water (0.39 M = 30 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06
Cat. # Quantity
11380 1 mg
21380 5 mg
41380 25 mg
51380 50 mg
61380 100 mg

Customers also purchased with this product
BDP FL NHS ester
Amino-reactive BDP FL, a very bright and photostable dye for fluorescein channel.

Cyanine5 DBCO
Cyanine5 dye with dibenzocyclooctyne (DBCO) functional group for copper free Click chemistry.

Cyanine5 NHS ester
Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.

Product citations

  1. Deckard, C.E.; Sczepanski, J.T. Reversible chromatin condensation by the DNA repair and demethylation factor thymine DNA glycosylase. Nucleic Acids Research, in press. doi: 10.1093/nar/gkab040
  2. Lapenta, F.; Aupič, J.; Vezzoli, M.; Strmšek, Ž.; Da Vela, S.; Svergun, D.I.; Carazo, J.M.; Melero, R.; Jerala, R. Self-assembly and regulation of protein cages from pre-organised coiled-coil modules. Nature Communications, 2021, 12, 939. doi: 10.1038/s41467-021-21184-6
  3. Aupič, J.; Strmšek, Ž.; Lapenta, F.; Pahovnik, D.; Pisanski, T.; Drobnak, I.; Ljubetič, A.; Jerala, R. Designed folding pathway of modular coiled-coil-based proteins. Nature Communications, 2021, 12, 940. doi: 10.1038/s41467-021-21185-5
  4. Tischer, D.; Weiner, O. Optogenetic Tuning of Protein-protein Binding in Bilayers Using LOVTRAP. Bio-protocol, 2020, 10(17), e3745. doi: 10.21769/BioProtoc.3745