Lumiprobe芘叠氮化物 1,Pyrene azide 1

Lumiprobe芘叠氮化物 1,Pyrene azide 1

Pyrene属于多环芳烃,拥有较强短波荧光。不像其他的荧光染料,多环芳烃类属于对微环境有较强灵敏度的荧光探针。因此,它的荧光性在极性和非极性环境中是不同的。其他的影响也可以被观察到。 当两个pyrenes靠的很近时,他们便表现出激发态。激发态形式很容易被观察到,使用荧光波谱图可以被定量估测。

Pyrene属于多环芳烃,拥有较强短波荧光。不像其他的荧光染料,多环芳烃类属于对微环境有较强灵敏度的荧光探针。因此,它的荧光性在极性和非极性环境中是不同的。其他的影响也可以被观察到。
当两个pyrenes靠的很近时,他们便表现出激发态。激发态形式很容易被观察到,使用荧光波谱图可以被定量估测。
Pyrene azide可以比较容易的应用于pyrene点击化学,对难以进行炔烃标记的分子进行标记。
它也可以将分子引入难以标记pyrene的探针。
这种叠氮染料含有亲水三甘醇链以缓解其固有的疏水性并促进在水中对生物分子的标记。
另两种点击化学用pyrene azides(23)。

Pyrene is a polyaromatic hydrocarbon with strong short-wavelength fluorescence. Unlike other fluorescent dyes, polyaromatic hydrocarbons are fluorescent probes with strong sensitivity to microenvironment. Thus, its fluorescence is different in polar, and nonpolar environments. Other effects can also be observed.

When two pyrenes are in close proximity, they form excimers. Excimer formation can be easily observed, and quantitatively estimated using fluorescent spectra.

Pyrene azide is a reagent for easy pyrene Click Chemistry labeling of any alkyne-bearing molecule. It allows to turn any molecule into pyrene-bearing probe.

This azide contains hydrophilic triethyleneglycol linker to mitigate intrinsic pyrene hydrophobicity, and facilitate attachment to biomolecules in aqueous solutions.

Another pyrene azide for Click Chemistry labeling is also available: Pyrene azide 2.

Structure of Pyrene azide 1

订购货号 产品名称及规格
A1530 Pyrene azide 1, 1 mg
B1530 Pyrene azide 1, 5 mg
C1530 Pyrene azide 1, 10 mg
D1530 Pyrene azide 1, 25 mg
E1530 Pyrene azide 1, 50 mg

General properties

Appearance: yellowish solid
Molecular weight: 402.45
Molecular formula: C23H22N4O3
Solubility: soluble in dichloromethane, chloroform, moderately soluble in DMSO, DMF, acetonitrile
Quality control: NMR聽1H (95%)
Storage conditions: Storage: 24 months after receival at -20掳C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
MSDS: Download

Spectral properties

Excitation maximum, nm: 343; 326; 313; 276; 265; 242; 234
Emission maximum, nm: 377; 397