Lumiprobe代理 D1540 AmdU (5-azidomethyl-2′-deoxyuridine), 25 mg
Azidomethyl-dU (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU.
Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.
General properties
| Appearance: | white / off white solid |
| Molecular weight: | 283.24 |
| Molecular formula: | C10H13N5O5 |
| IUPAC name: | 5-Azidomethyl-2′-deoxyuridine |
| Solubility: | good in water, alcohols, DMSO, DMF |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
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