Lumiprobe Cyanine5 DBCO 染料

Lumiprobe Cyanine5 DBCO 染料

A derivative of Cyanine5 red-emitting fluorophore possessing DBCO (dibenzocyclooctyne, also known as ADIBO, azodibenzocyclooctyne) group for copper free Click chemistry.

Strained cycloalkynes, such as cyclooctynes, react with azides very rapidly in the absence of copper catalyst in a strain promoted alkyne azide cycloaddition (spAAC). This reaction is very fast, mild, and biocompatible.

Compared to other cycloalkynes, DBCO provide among the fastest reaction kinetics, still possessing good stability.

一种具有 DBCO(二苯并环辛炔,也称为 ADIBO,偶氮二苯并环辛炔)基团的 Cyanine5 发红光荧光团的衍生物,用于无铜点击化学。

在不存在铜催化剂的情况下,在应变促进的炔烃叠氮化物环加成 (spAAC) 中,应变的环炔烃,例如环辛炔,与叠氮化物反应非常迅速。 该反应非常快速、温和且具有生物相容性。

与其他环炔烃相比,DBCO 提供了最快的反应动力学,但仍具有良好的稳定性。

货号 规格 货期
A30F0 1 mg in stock
B30F0 5 mg in stock
C30F0 10 mg in stock
D30F0 25 mg in stock
E30F0 50 mg in stock
F30F0 100 mg in stock

General properties

Appearance: dark blue solid
Mass spec M+ increment: 928.4
Molecular weight: 929.03
Molecular formula: C53H59N4F6O2P
Solubility: good in DMF, DMSO, chlorinated organic solvents, practically insoluble in water (<1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

Product citations

  1. Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. Journal of Enzyme Inhibition and Medicinal Chemistry2021, 36(1), 85–97. doi: 10.1080/14756366.2020.1841182
  2. Qiu, C.-X.; Bai, X.-F.; Shen, Y.; Zhou, Z.; Pan, L.-Q.; Xu, Y.-C.; Zhao, W.-B.; Chen, S.-Q. Specific Inhibition of Tumor Growth by T Cell Receptor-Drug Conjugates Targeting Intracellular Cancer-Testis Antigen NY-ESO-1/LAGE-1. Bioconjugate Chemistry2020, 31(12), 2767–2778. doi: 10.1021/acs.bioconjchem.0c00548
  3. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics2020, 221(19), 2000156. doi: 10.1002/macp.202000156
  4. Liu, W.; Zhao, W.; Bai, X.; Jin, S.; Li, Y.; Qiu, C.; Pan, L.; Ding, D.; Xu, Y.; Zhou, Z.; Chen, S. High antitumor activity of Sortase A-generated anti-CD20 antibody fragment drug conjugates. European Journal of Pharmaceutical Sciences2019, 134, 81–92. doi: 10.1016/j.ejps.2019.04.015

Lumiprobe Cyanine5.5 DBCO

Lumiprobe Cyanine5.5 DBCO

上海金畔生物代理Lumiprobe品牌荧光染料等,我们将竭诚为您服务,欢迎访问Lumiprobe官网或者咨询我们获取更多相关Lumiprobe品牌产品信息。

Strain promoted alkyne azide cycloaddition (spAAc) between strained cycloalkynes and azides is a useful bioconjugation method that eliminates the need for copper catalyst necessary for classical CuAAc Click chemistry.

Cyanine5.5 DBCO is a cyclooctyne product containing Cyanine5.5 fluorescent dye. This fluorophore is used in bioimaging, biodistribution studies, and microscopy.

Cyanine5.5 DBCO can be used to conjugate the fluorophore with various azides.

应变环炔烃和叠氮化物之间的应变促进炔烃叠氮环加成 (spAAc) 是一种有用的生物共轭方法,它消除了对经典 CuAAc 点击化学所需的铜催化剂的需求。

Cyanine5.5 DBCO 是一种含有 Cyanine5.5 荧光染料的环辛炔产品。 这种荧光团用于生物成像、生物分布研究和显微镜检查。

Cyanine5.5 DBCO 可用于将荧光团与各种叠氮化物结合。

General properties

Appearance: dark colored solid
Mass spec M+ increment: 882.5
Molecular weight: 1029.14
CAS number: 2643308-61-4
Molecular formula: C61H63N4F6O2P
Solubility: good in DMF, DMSO, chlorinated organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

A70F0 1 mg in stock
B70F0 5 mg in stock
C70F0 10 mg in stock
D70F0 25 mg in stock
E70F0 50 mg in stock
F70F0 100 mg in stock

Product citations  参考文献

  1. Fornasier, M.; Porcheddu, A.; Casu, A.; Raghavan, S.R.; Jönsson, P.; Schillén, K.; Murgia, S. Surface-modified nanoerythrosomes for potential optical imaging diagnostics. Journal of Colloid and Interface Science2021, 582, 246–253. doi: 10.1016/j.jcis.2020.08.032
  2. Lim, Y.G.; Kim, H.J.; Kim, J.W.; Park, K. Calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging. Journal of Industrial and Engineering Chemistry2020, 89, 442–447. doi: 10.1016/j.jiec.2020.06.018

Lumiprobe Cyanine2 NHS ester minimal dye

Lumiprobe Cyanine2 NHS ester minimal dye

yanine2 minimal dye for protein labeling, an equivalent of Cy2® NHS ester minimal dye.

This reagent is specially quantified – each package contains specified amount of NHS ester with quantity variation within 10%.

用于蛋白质标记的Cyanine2微量染料,相当于Cy2 NHS酯微量染料。

该试剂是特别量化的-每个包装含有规定量的NHS酯,数量变化在10%以内。

Cat. # Quantity
1A041 5 nmol
2A041 10 nmol
3A041 25 nmol

General properties

Appearance: yellow solid
Quality control: NMR 1H, HPLC-MS, functional testing
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

Excitation/absorption maximum, nm: 490
Emission maximum, nm: 510

Product citations

  1. Shikov, A.E.; Malovichko, Y.V.; Lobov, A.A.; Belousova, M.E.; Nizhnikov, A.A.; Antonets, K.S. The Distribution of Several Genomic Virulence Determinants Does Not Corroborate the Established Serotyping Classification of Bacillus thuringiensisInternational Journal of Molecular Sciences2021, 22(5), 2244. doi: 10.3390/ijms22052244
  2. Serteyn, L.; Bosquee, E.; Delatour, A.; Rubio-Melendez, M.E.; Vega-Muñoz, K.V.; Ramirez, C.C.; Francis, F. Multi-approach comparative study of the two most prevalent genotypes of pea aphid Acyrthosiphon pisum (Hemiptera: Aphididae) in Chile. Entomological Science2021, 24(1), 55–67. doi: 10.1111/ens.12436
  3. Tamošiūnė, I.; Gelvonauskienė, D.; Haimi, P.; Mildažienė, V.; Koga, K.; Shiratani, M.; Baniulis, D. Cold Plasma Treatment of Sunflower Seeds Modulates Plant-Associated Microbiome and Stimulates Root and Lateral Organ Growth. Frontiers in Plant Science2020, 11, 568924. doi: 10.3389/fpls.2020.568924
  4. Valadares, R.B.S.; Perotto, S.; Lucheta, A.R.; Santos, E.C.; Oliveira, R.M.; Lambais, M.R. Proteomic and Transcriptomic Analyses Indicate Metabolic Changes and Reduced Defense Responses in Mycorrhizal Roots of Oeceoclades maculata (Orchidaceae) Collected in Nature. Journal of Fungi2020, 6(3), 148. doi: 10.3390/jof6030148

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正文中列出的所有试剂只能用于测试或研究,不能作为”药品”,”食品”,”家庭用品”等使用。
我司所销售的化学试剂、原料等所有产品(包括但不限于抗生素类、蛋白质类、试剂盒类产品等)仅限用于科学研究用途,不得作用于人体。

Lumiprobe Cy染料1497-100mg sulfo-Cyanine7 dicarboxylic acid, 100 mg

Lumiprobe Cy染料1497-100mg sulfo-Cyanine7 dicarboxylic acid, 100 mg

Sulfo-Cyanine7 dicarboxylic acid (Сy7 analogue) is a water soluble, bifunctional NIR dye derivative bearing two carboxylic acid functional groups.

Structure of sulfo-Cyanine7 dicarboxylic acid

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
CF260: 0.04
CF280: 0.04

General properties

Appearance: dark green solid
Molecular weight: 847.09
Molecular formula: C42H51N2KO10S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
Cat. # Quantity
1497-1mg 1 mg
1497-5mg 5 mg
1497-25mg 25 mg
1497-50mg 50 mg
1497-100mg 100 mg

Customers also purchased with this product
Cyanine7 dicarboxylic acid
Cyanine7 dicarboxylic acid is a bifunctional dye molecule possessing two carboxylic acid groups.

Sulfo-Cyanine7 azide
Water-soluble NIR fluorescent dye azide for Click chemistry

Sulfo-Cyanine7.5 dicarboxylic acid
Sulfo-Cyanine7.5 dicarboxylic acid is a bifunctional cyanine dye with two carboxylic acid (COOH) groups. The molecule can be used to construct cross conjugates containing a near infrared emitting fluorophore.

Lumiprobe Cy染料61390 Sulfo-Cyanine3 carboxylic acid, 100 mg

Lumiprobe Cy染料61390 Sulfo-Cyanine3 carboxylic acid, 100 mg

Sulfo-Cyanine3 carboxylic acid

free express shipping.

Water soluble sulfo-Cyanine3 dye, free unactivated monofunctional carboxylic acid. This reagent can be used as a reference fluorophore for Cy3® detection channel, as a control in experiments with other sulfo-Cyanine3 labeled products. Carboxylic acid can be also activated with carbodiimides.

Absorbance and emission spectra are identical with Cy3® fluorophore.

sulfo-Cy3 carboxylic acid fluorophore structure

General properties

Appearance: dark red crystals
Molecular weight: 654.84
CAS number: 1121756-11-3 (inner salt); 1941997-61-0 (sodium salt)
Molecular formula: C30H35N2KO8S2
IUPAC name: 3H-​Indolium, 2-​[3-​[1-​(5-​carboxypentyl)​-​1,​3-​dihydro-​3,​3-​dimethyl-​5-​sulfo-​2H-​indol-​2-​ylidene]​-​1-​propen-​1-​yl]​-​1,​3,​3-​trimethyl-​5-​sulfo-​, inner salt, potassium salt
Solubility: Well soluble in water, DMF, DMSO (0.55 M = 360 g/L). Practically insoluble in non-polar organic solvents.
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

Spectral properties

Excitation maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06
Cat. # Quantity
11390 1 mg
21390 5 mg
41390 25 mg
51390 50 mg
61390 100 mg

Customers also purchased with this product
Cyanine3 maleimide
Cyanine3 maleimide is a thiol mono reactive dye.

Sulfo-Cyanine5.5 maleimide
Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Cyanine3 amine
Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Product citations

  1. Vallmitjana, A.; Torrado, B.; Dvornikov, A.; Ranjit, S.; Gratton, E. Blind Resolution of Lifetime Components in Individual Pixels of Fluorescence Lifetime Images Using the Phasor Approach. Journal of Physical Chemistry B2020, 124(45), 10126–10137. doi: 10.1021/acs.jpcb.0c06946
  2. Cho, U.; Riordan, D.P.; Ciepla, P.; Kocherlakota, K.S.; Chen, J.K.; Harbury, P.B. Ultrasensitive optical imaging with lanthanide lumiphores. Nature Chemical Biology2018, 14(1), 15–21. doi: 10.1038/nchembio.2513
  3. Spears, B.R.; Marin, M.A.; Chaker, A.N.; Lampley, M.W.; Harth, E. Precise Microscale Polymeric Networks through Piezoelectronic Inkjet Printing. ACS Biomaterials Science & Engineering2016, 2(8), 1265–1272. doi: 10.1021/acsbiomaterials.6b00175

Lumiprobe Cy染料613C0 Sulfo-Cyanine3 amine, 100 mg

Lumiprobe Cy染料613C0 Sulfo-Cyanine3 amine, 100 mg

A water soluble dye with amino group, useful for the conjugation with electrophiles, and for enzymatic transamination labeling.

Sulfo-Cyanine3 is a sulfonated analog of Cy3®, which is compatible with various fluorescence measuring equipment. The dye is highly photostable. It is also easily detectable by naked eye.

Sulfo-Cy3 amine structure

General properties

Appearance: dark red solid
Molecular weight: 714.94
CAS number: 2183440-43-7
Molecular formula: C36H50N4O7S2
IUPAC name: 3H-​Indolium, 1-​[6-​[(6-​aminohexyl)​amino]​-​6-​oxohexyl]​-​2-​[3-​(1,​3-​dihydro-​1,​3,​3-​trimethyl-​5-​sulfo-​2H-​indol-​2-​ylidene)​-​1-​propen-​1-​yl]​-​3,​3-​dimethyl-​5-​sulfo-​, inner salt
Solubility: well soluble in water (0.49 M = 350 g/L), alcohols, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06
Cat. # Quantity
113C0 1 mg
213C0 5 mg
413C0 25 mg
513C0 50 mg
613C0 100 mg

Product citations

  1. Bos, I.; Timmerman, M.; Sprakel, J. FRET-Based Determination of the Exchange Dynamics of Complex Coacervate Core Micelles. Macromolecules2021, 54(1), 398–411. doi: 10.1021/acs.macromol.0c02387
  2. Zhang, Q.; Scigliano, A.; Biver, T.; Pucci, A.; Swager, T.M. Interfacial Bioconjugation on Emulsion Droplet for Biosensors. Bioorganic & Medicinal Chemistry2018, 26(19), 5307–5313. doi: 10.1016/j.bmc.2018.04.020
  3. Sobotzki, N.; Schafroth, M.A.; Rudnicka, A.; Koetemann, A.; Marty, F.; Goetze, S.; Yamauchi, Y.; Carreira, E.M.; Wollscheid, B. HATRIC-based identification of receptors for orphan ligands. Nature Communications2018, 9, 1519. doi: 10.1038/s41467-018-03936-z

Lumiprobe代理 41090 Cyanine3 carboxylic acid, 25 mg

Lumiprobe代理 41090 Cyanine3 carboxylic acid, 25 mg

Free Cyanine3 carboxylic acid (Cy3® carboxylic acid analog), non-activated dye. Non-sulfonated reagent, with good solubility in organic solvents, and limited aquous solubility. The dye can be used as a non-reactive fluorophore, for control experiments, and for calibration.

For coupling with amines, and labeling, consider using Cyanine3 NHS ester, or water-soluble sulfo-Cyanine3 NHS ester.

Cy3 free carboxylic acid structure

General properties

Appearance: red powder
Molecular weight: 493.08
CAS number: 1361402-15-4 (inner salt), 1032678-01-5 (chloride), 1251915-29-3 (iodide)
Molecular formula: C30H37ClN2O2
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), poorly soluble in water (1.8 g/L = 4.0 mM)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

Excitation maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09
Cat. # Quantity
11090 1 mg
21090 5 mg
41090 25 mg
51090 50 mg
61090 100 mg

Customers also purchased with this product
Sulfo-Cyanine5.5 NHS ester
Water soluble, sulfonated, far-red sulfo-Cyanine5.5 dye in the form of NHS ester.

BDP TR NHS ester
BDP TR is a borondipyrromethene dye for Texas Red channel. A bright and photostable fluorophore with high quantum yield.

Cyanine3 amine
Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Product citations

  1. Nam, J.; Lim, H.-K.; Kim, N.H.; Park, J.K.; Kang, E.S.; Kim, Y.-T.; Heo, C.; Lee, O.-S.; Kim, S.-G.; Yun, W.S.; Suh, M.; Kim, Y.H. Supramolecular Peptide Hydrogel-Based Soft Neural Interface Augments Brain Signals through Three-Dimensional Electrical Network. ACS Nano2020, 14(1), 664–675. doi: 10.1021/acsnano.9b07396
  2. Deshmukh, R.; Biehs, S.-A.; Khwaja, E.; Galfsky, T.; Agarwal, G.S.; Menon, V.M. Long-range resonant energy transfer using optical topological transitions in metamaterials. ACS Photonics2018, 5(7), 2737–2741. doi: 10.1021/acsphotonics.8b00484
  3. Mattila, J.T.; Beaino, W.; Maiello, P.; Coleman, M.T.; White, A.G.; Scanga, C.A.; Flynn, J.A.; Anderson, C.J. Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin α4β1-Expressing Immune Cells. Journal of immunology2017, 199(2), 806–815. doi: 10.4049/jimmunol.1700231
  4. Soni, K.S.; Lei, F.; Desale, S.S.; Marky, L.A.; Cohen, S.M.; Bronich, T.K. Tuning polypeptide-based micellar carrier for efficient combination therapy of ErbB2-positive breast cancer. Journal of Controlled Release2017, 264, 276–287. doi: 10.1016/j.jconrel.2017.08.038

Lumiprobe代理 1171-1mL BDP TR methyl ester, 5 mM in DMSO

Lumiprobe代理 1171-1mL BDP TR methyl ester, 5 mM in DMSO

A solution of BDP TR methyl ester, a counterstain for cells expressing green fluorescent protein (GFP).

This is a cell-permeable dye that stains mitochondria and endomembranous organelles, but not plasma membrane. The dye is compatible with formaldehyde fixation.

Structure of BODIPY TR methyl ester

General properties

Appearance: blue solution
Molecular weight: 438.26
Molecular formula: C22H17BF2N2O3S
Quality control: NMR 1H, HPLC-MS (95%)

Spectral properties

Excitation maximum, nm: 589
ε, L⋅mol−1⋅cm−1: 69000
Emission maximum, nm: 616
Fluorescence quantum yield: 0.9
1171-1mL 1 mL

Customers also purchased with this product
BDP FL carboxylic acid
Borondipyrromethene dye for fluorescein (FAM) channel, free unactivated carboxylic acid useful as a negative control, and for the calibration.

BDP 630/650 carboxylic acid
BDP 630/650 is a bright fluorophore for far red part of the spectrum. This dye is perfect for microscopy and fluorescence polarization assays. This is a carboxylic acid that can be activated for the coupling, or used as a control.

BDP 493/503 lipid stain
BDP 493/503 is a lipophilic borondipyrromethene dye for the staining and tracing of lipids and oils.

Lumiprobe代理 55430 BDP 630/650 azide, 50 mg

Lumiprobe代理 55430 BDP 630/650 azide, 50 mg

BDP 630/650 azide is a bright and photostable dye azide for the far red region of the spectrum, for labeling using Click chemistry.

This dye possesses a relatively long lifetime of the excited state, and can therefore be used for fluorescence polarization experiments.

Structure of BDP 630/650 azide

General properties

Appearance: dark colored powder
Mass spec M+ increment: 532.2
Molecular weight: 532.37
CAS number: 2183473-22-3
Molecular formula: C26H23N6BF2O2S
IUPAC name: Boron, [N-​(3-​azidopropyl)​-​2-​[4-​[2-​[5-​[[5-​(2-​thienyl)​-​2H-​pyrrol-​2-​ylidene-​κN]​methyl]​-​1H-​pyrrol-​2-​yl-​κN]​ethenyl]​phenoxy]​acetamidato]​difluoro-​, (T-​4)​- Coordination Compound
Solubility: good in DMSO, DMF, acetonitrile, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

Excitation maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035
Cat. # Quantity
15430 1 mg
25430 5 mg
35430 10 mg
45430 25 mg
55430 50 mg

Customers also purchased with this product
BDP 630/650 amine
BDP 630/650 is a far red emitting fluorophore for Cyanine5 channel. This fluorophore is based on BDP (borondipyrromethene) core, which provides high quantum yield and photostability. This is an amine derivative of this dye.

Sulfo-Cyanine5.5 NHS ester
Water soluble, sulfonated, far-red sulfo-Cyanine5.5 dye in the form of NHS ester.

BDP 650/665 azide
BDP 650/665 is a red-emitting borondipyrromethene dye. This azide derivative can be conjugated with alkynes and cycloalkynes.

Lumiprobe代理 61470 BDP FL hydrazide, 100 mg

Lumiprobe代理 61470 BDP FL hydrazide, 100 mg

BDP FL is a bright and photostable dye for FAM channel. It possesses great photostability, quantum yield approaching unity. This dye is well-suited for microscopy and fluorescence polarization assays.

Hydrazide group provides easy conjugation with carbonyl compounds (aldehydes, and ketones).

Structure of BODIPY FL hydrazide

General properties

Appearance: brown to orange solid
Molecular weight: 342.58
CAS number: 2183473-45-0 (hydrochloride); 178388-71-1; 2256724-38-4
Molecular formula: C14H18BClF2N4O
Solubility: poorly soluble in water (20.2 mM = 6.94 g/L), soluble in polar (DMSO, DMF) organic solvents, methanol, moderately soluble in acetonitrile, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

Excitation maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027
Cat. # Quantity
11470 1 mg
21470 5 mg
41470 25 mg
51470 50 mg
61470 100 mg

Customers also purchased with this product
Cyanine5 hydrazide
Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.

BDP 581/591 hydrazide
BDP 581/591 is a multi-purpose dye with bright emission. This is a hydrazide dye for the conjugation with aldehydes and ketones.

Sulfo-Cyanine5 NHS ester
Water-soluble Cyanine 5 succinimide ester.

Product citations

  1. Roloff, A.; Nirmalananthan-Budau, N.; Rühle, B.; Borcherding, H.; Thiele, T.; Schedler, U.; Resch-Genger, U. Quantification of Aldehydes on Polymeric Microbead Surfaces via Catch and Release of Reporter Chromophores. Analytical Chemistry2019, 91(14), 8827–8834. doi: 10.1021/acs.analchem.8b05515
  2. Liu, R.; Vairaprakash, P.; Lindsey, J.S. Self-assembly with fluorescence readout in a free base dipyrrin–polymer triggered by metal ion binding in aqueous solution. New Journal of Chemistry2019, 43(24), 9711–9724. doi: 10.1039/c9nj01787a