Lumiprobe Sulfo-Cy7 NHS ester 磺酸基-Cy7-N-羟基琥珀酰亚胺酯 65320 100 mg
Water soluble near infrared dye sulfo-Cyanine7, an amine-reactive succinimide ester.
Sulfo-Cyanine7 is an improved analog of Cy7® fluorophore with quantum yield improved by 20%, and higher photostability. This fluorescent dye is especially useful for NIR imaging.
Near infrared fluorescent imaging takes advantage of transparency of biological tissues at particular range of wavelengths. The method is non-destructive, and allows to monitor distribution of various labeled molecules in live organisms.
Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and drug design related experiments.
This reagent has high water solubility, and is especially useful for the labeling of delicate proteins, and proteins prone to denaturation. Non-sulfonated Cyanine7 NHS ester soluble in organic phase is also available.
General properties
| Appearance: | dark green powder |
| Molecular weight: | 844.05 |
| CAS number: | 1603861-95-5 (potassium salt); 1604244-45-2 (inner salt); 477908-53-5 (N-Ethyl) |
| Molecular formula: | C41H46N3KO10S2 |
| Solubility: | good in water, DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
Spectral properties
| Excitation maximum, nm: | 750 |
| ε, L⋅mol−1⋅cm−1: | 240600 |
| Emission maximum, nm: | 773 |
| CF260: | 0.04 |
| CF280: | 0.04 |
15320 1 mg
25320 5 mg
45320 25 mg
55320 50 mg
65320 100 mg
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Product citations
- Trac, N.; Chen, L.-Y.; Zhang, A.; Liao, C.-P.; Poon, C.; Wang, J.; Ando, Y.; Joo, J.; Garri, C.; Shen, K.; Kani, K.; Gross, M.E.; Chung, E.J. CCR2-targeted micelles for anti-cancer peptide delivery and immune stimulation. Journal of Controlled Release, 2021, 329, 614–623. doi: 10.1016/j.jconrel.2020.09.054
- González, L.F.; Acuña, E.; Arellano, G.; Morales, P.; Sotomayor, P.; Oyarzun-Ampuero, F.; Naves, R. Intranasal delivery of interferon-β-loaded nanoparticles induces control of neuroinflammation in a preclinical model of multiple sclerosis: A promising simple, effective, non-invasive, and low-cost therapy. Journal of Controlled Release, 2021, 331, 443–459. doi: 10.1016/j.jconrel.2020.11.019
- Shapoval, O.; Oleksa, V.; Šlouf, M.; Lobaz, V.; Trhlíková, O.; Filipová, M.; Janoušková, O.; Engstová, H.; Pankrác, J.; Modrý, A.; Herynek, V.; Ježek, P.; Šefc, L.; Horák, D. Colloidally Stable P(DMA-AGME)-Ale-Coated Gd(Tb)F3:Tb3+(Gd3+),Yb3+,Nd3+ Nanoparticles as a Multimodal Contrast Agent for Down- and Upconversion Luminescence, Magnetic. Nanomaterials, 2021, 11(1), 230. doi: 10.3390/nano11010230
- Molotkov, A.; Bhatt, N.; Doubrovin, M.; Castrillon, J.; Massa, C.; Gerber, A.; D’Armiento, J.; Goldklang, M.; Mintz, A. Multimodality molecular imaging of the alveolar-capillary barrier in lung disease using albumin based optical and PET tracers. Molecular Biomedicine, 2020, 1(1), 17. doi: 10.1186/s43556-020-00020-1