Lumiprobe代理 41720 Alkyne NHS ester (hexynoic acid NHS ester), 25 mg
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Alkyne NHS ester for the modification of biomolecules. Alkyne groups for copper catalyzed Click Chemistry reaction are nearly never encountered in natural molecules. However, this NHS ester allows to attach alkyne groups to amino groups, which are ubiquitous in nature, and which are present in proteins, peptides, synthetic amino-DNA and numerous small molecules. Alkyne groups can be subsequently modified and conjugated by Copper catalyzed Click chemistry.
General properties
| Appearance: | yellowish oil / off white crystals |
| Mass spec M+ increment: | 94.0 |
| Molecular weight: | 209.20 |
| CAS number: | 906564-59-8 |
| Molecular formula: | C10H11NO4 |
| IUPAC name: | 5-Hexynoic acid, 2,5-dioxo-1-pyrrolidinyl ester |
| Solubility: | good in organic solvents (DMF, DMSO, DCM) |
| Quality control: | NMR 1H 95+% |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| Cat. # | Quantity |
| 41720 | 25 mg |
| 51720 | 50 mg |
| 61720 | 100 mg |
| 91720 | 1 g |
Product citations
- Kleinpenning, F.; Steigenberger, B.; Wu, W.; Heck, A.J.R. Fishing for newly synthesized proteins with phosphonate-handles. Nature Communications, 2020, 11, 3244. doi: 10.1038/s41467-020-17010-0