Lumiprobe代理 22860 Alkyne CPG modifier 500, 250 mg
High loading controlled pore glass solid support for the synthesis of oligonucleotides with 3′-alkyne group. With this solid support, synthesis of oligos of up to 50 bases is possible.
Terminal alkyne group can be modified by copper catalyzed Click chemistry (see our recommended protocol for oligonucleotide modification).
This solid support is compatible with standard oligonucleotide deblocking conditions. No special deblocking is required.
General properties
Appearance: | off-white beads |
Quality control: | NMR 1H and HPLC (95%) of bound reagent, loading measurement |
Storage conditions: | Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate. |
Oligo synthesis details
Pore size, Å: | 500 |
Typical loading, umol/g: | 70−90 |
Coupling conditions: | standard coupling, identical to normal nucleobases |
Cleavage conditions: | ammonia, 2 h at room temperature |
Deprotection conditions: | identical to protected nucleobases |
Cat. # | Quantity |
12860 | 100 mg |
22860 | 250 mg |
32860 | 500 mg |
42860 | 1 g |
52860 | 5 g |