Lumiprobe代理 22860 Alkyne CPG modifier 500, 250 mg

Lumiprobe代理 22860 Alkyne CPG modifier 500, 250 mg

High loading controlled pore glass solid support for the synthesis of oligonucleotides with 3′-alkyne group. With this solid support, synthesis of oligos of up to 50 bases is possible.

Terminal alkyne group can be modified by copper catalyzed Click chemistry (see our recommended protocol for oligonucleotide modification).

This solid support is compatible with standard oligonucleotide deblocking conditions. No special deblocking is required.

Alkyne CPG modifier controlled pore glass structure

General properties

Appearance: off-white beads
Quality control: NMR 1H and HPLC (95%) of bound reagent, loading measurement
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

Oligo synthesis details

Pore size, Å: 500
Typical loading, umol/g: 70−90
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases
Cat. # Quantity
12860 100 mg
22860 250 mg
32860 500 mg
42860 1 g
52860 5 g