Lumiprobe Cyanine5.5 DBCO

Lumiprobe Cyanine5.5 DBCO


Strain promoted alkyne azide cycloaddition (spAAc) between strained cycloalkynes and azides is a useful bioconjugation method that eliminates the need for copper catalyst necessary for classical CuAAc Click chemistry.

Cyanine5.5 DBCO is a cyclooctyne product containing Cyanine5.5 fluorescent dye. This fluorophore is used in bioimaging, biodistribution studies, and microscopy.

Cyanine5.5 DBCO can be used to conjugate the fluorophore with various azides.

应变环炔烃和叠氮化物之间的应变促进炔烃叠氮环加成 (spAAc) 是一种有用的生物共轭方法,它消除了对经典 CuAAc 点击化学所需的铜催化剂的需求。

Cyanine5.5 DBCO 是一种含有 Cyanine5.5 荧光染料的环辛炔产品。 这种荧光团用于生物成像、生物分布研究和显微镜检查。

Cyanine5.5 DBCO 可用于将荧光团与各种叠氮化物结合。

General properties

Appearance: dark colored solid
Mass spec M+ increment: 882.5
Molecular weight: 1029.14
CAS number: 2643308-61-4
Molecular formula: C61H63N4F6O2P
Solubility: good in DMF, DMSO, chlorinated organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

A70F0 1 mg in stock
B70F0 5 mg in stock
C70F0 10 mg in stock
D70F0 25 mg in stock
E70F0 50 mg in stock
F70F0 100 mg in stock

Product citations  参考文献

  1. Fornasier, M.; Porcheddu, A.; Casu, A.; Raghavan, S.R.; Jönsson, P.; Schillén, K.; Murgia, S. Surface-modified nanoerythrosomes for potential optical imaging diagnostics. Journal of Colloid and Interface Science2021, 582, 246–253. doi: 10.1016/j.jcis.2020.08.032
  2. Lim, Y.G.; Kim, H.J.; Kim, J.W.; Park, K. Calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging. Journal of Industrial and Engineering Chemistry2020, 89, 442–447. doi: 10.1016/j.jiec.2020.06.018