Lumiprobe代理 410C0 Cyanine3 amine, 25 mg

Lumiprobe代理 410C0 Cyanine3 amine, 25 mg

Cyanine3 amine is a functionalized cyanine dye containing a free amino group. Cyanine3 is an analog of Cy3®.

Amino group of this reagent can be conjugated with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides.

The amino dye is supplied in salt form, and possesses some aqueous solubility.

Cyanine3 amine structure

General properties

Appearance: red powder
Molecular weight: 627.73
CAS number: 2247688-56-6
Molecular formula: C36H52Cl2N4O
IUPAC name: 3H-​Indolium, 1-​[6-​[(6-​aminohexyl)​amino]​-​6-​oxohexyl]​-​2-​[3-​(1,​3-​dihydro-​1,​3,​3-​trimethyl-​2H-​indol-​2-​ylidene)​-​1-​propen-​1-​yl]​-​3,​3-​dimethyl-​, chloride, hydrochloride (1:1:1)
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09
Cat. # Quantity
110C0 1 mg
210C0 5 mg
410C0 25 mg
510C0 50 mg
610C0 100 mg

Product citations

  1. Wang, Y.; van Steenbergen, M.J.; Beztsinna, N.; Shi, Y.; Lammers, T.; van Nostrum, C.F.; Hennink, W.E. Biotin-decorated all-HPMA polymeric micelles for paclitaxel delivery. Journal of Controlled Release2020, 328, 970–984. doi: 10.1016/j.jconrel.2020.09.013
  2. Hifni, B.; Khan, M.; Devereux, S.J.; Byrne, M.H.; Quinn, S.J.; Simpson, J.C. Investigation of the cellular destination of fluorescently labelled carbon nanohorns in cultured cells. ACS Applied Bio Materials2020, 3(10), 6790–6801. doi: 10.1021/acsabm.0c00748
  3. Teng, F.; Wu, X.; Libera, M.R. Chemical Orthogonality in Surface-Patterned Poly(ethylene glycol) Microgels. Langmuir2020, 36(35), 10622–10627. doi: 10.1021/acs.langmuir.0c02172
  4. Zaw Thin, M.; Allan, H.; Bofinger, R.; Kostelec, T.D.; Guillaume, S.; Connell, J.J.; Patrick, P.S.; Hailes, H.C.; Tabor, A.B.; Lythgoe, M.F.; Stuckey, D.J.; Kalber, T.L. Multi-modal imaging probe for assessing the efficiency of stem cell delivery to orthotopic breast tumours. Nanoscale2020, 12(31), 16570–16585. doi: 10.1039/d0nr03237a