Lumiprobe代理 41090 Cyanine3 carboxylic acid, 25 mg

Lumiprobe代理 41090 Cyanine3 carboxylic acid, 25 mg

Free Cyanine3 carboxylic acid (Cy3® carboxylic acid analog), non-activated dye. Non-sulfonated reagent, with good solubility in organic solvents, and limited aquous solubility. The dye can be used as a non-reactive fluorophore, for control experiments, and for calibration.

For coupling with amines, and labeling, consider using Cyanine3 NHS ester, or water-soluble sulfo-Cyanine3 NHS ester.

Cy3 free carboxylic acid structure

General properties

Appearance: red powder
Molecular weight: 493.08
CAS number: 1361402-15-4 (inner salt), 1032678-01-5 (chloride), 1251915-29-3 (iodide)
Molecular formula: C30H37ClN2O2
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), poorly soluble in water (1.8 g/L = 4.0 mM)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

Excitation maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09
Cat. # Quantity
11090 1 mg
21090 5 mg
41090 25 mg
51090 50 mg
61090 100 mg

Customers also purchased with this product
Sulfo-Cyanine5.5 NHS ester
Water soluble, sulfonated, far-red sulfo-Cyanine5.5 dye in the form of NHS ester.

BDP TR NHS ester
BDP TR is a borondipyrromethene dye for Texas Red channel. A bright and photostable fluorophore with high quantum yield.

Cyanine3 amine
Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Product citations

  1. Nam, J.; Lim, H.-K.; Kim, N.H.; Park, J.K.; Kang, E.S.; Kim, Y.-T.; Heo, C.; Lee, O.-S.; Kim, S.-G.; Yun, W.S.; Suh, M.; Kim, Y.H. Supramolecular Peptide Hydrogel-Based Soft Neural Interface Augments Brain Signals through Three-Dimensional Electrical Network. ACS Nano2020, 14(1), 664–675. doi: 10.1021/acsnano.9b07396
  2. Deshmukh, R.; Biehs, S.-A.; Khwaja, E.; Galfsky, T.; Agarwal, G.S.; Menon, V.M. Long-range resonant energy transfer using optical topological transitions in metamaterials. ACS Photonics2018, 5(7), 2737–2741. doi: 10.1021/acsphotonics.8b00484
  3. Mattila, J.T.; Beaino, W.; Maiello, P.; Coleman, M.T.; White, A.G.; Scanga, C.A.; Flynn, J.A.; Anderson, C.J. Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin α4β1-Expressing Immune Cells. Journal of immunology2017, 199(2), 806–815. doi: 10.4049/jimmunol.1700231
  4. Soni, K.S.; Lei, F.; Desale, S.S.; Marky, L.A.; Cohen, S.M.; Bronich, T.K. Tuning polypeptide-based micellar carrier for efficient combination therapy of ErbB2-positive breast cancer. Journal of Controlled Release2017, 264, 276–287. doi: 10.1016/j.jconrel.2017.08.038