Lumiprobe代理 21050 Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO, 1.5 mL

Lumiprobe代理 21050 Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO, 1.5 mL

Copper (II)-TBTA complex is a component of catalyst used for Click Chemistry conjugation reaction. Actual catalyst contains Cu(I), but this reagent cannot be stored, and should be generated from Copper(II)-TBTA complex in situ by reduction. To activate this catalyst, reductant such as ascorbic acid should be added to reaction mixture.

General properties

Appearance: blue solution
Molecular weight: 690.23
Molecular formula: C30H30CuN10O4S
Quality control: functional testing (Click Chemistry)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.

Copper(II)-TBTA complex structure

Cat. # Quantity
21050 1.5 mL

Product citations

  1. Wang, Y.; Kathiresan, V.; Chen, Y.; Hu, Y.; Jiang, W.; Bai, G.; Liu, G.; Qin, P.Z.; Fang, X. Posttranscriptional Site-Directed Spin Labeling of Large RNAs with an Unnatural Base Pair System Under Non-Denaturing Conditions. ChemRxiv, preprint. doi: 10.26434/chemrxiv.12058914
  2. Novopashina, D.S.; Vorobyeva, M.A.; Lomzov, A.A.; Silnikov, V.N.; Venyaminova, A.G. Terminal Mono- and Bis-Conjugates of Oligonucleotides with Closo-Dodecaborate: Synthesis and Physico-Chemical Properties. International Journal of Molecular Sciences2021, 22(1), 182. doi: 10.3390/ijms22010182
  3. Zhao, Meng and Börner, Richard and Sigel, Roland K. O. and Freisinger, Eva. Site-Specific Dual-Color Labeling of Long RNAs. Methods in Molecular Biology2020, 2106, 253–270. doi: 10.1007/978-1-0716-0231-7_16
  4. Blanchard, A.T.; Bazrafshan, A.S.; Yi, J.; Eisman, J.T.; Yehl, K.M.; Bian, T.; Mugler, A.; Salaita, K. Highly Polyvalent DNA Motors Generate 100+ pN of Force via Autochemophoresis. Nano Letters2019, 19(10), 6977–6986. doi: 10.1021/acs.nanolett.9b02311